Encodes ROTUNDIFOLIA4, a member of the seed plant-specific family of small peptides, RTFL (ROT FOUR LIKE), characterised by the presence of a 29-amino acid domain: RTF. Expressed in shoot apices, young leaves and flowers. Involved in controlling polarity-dependent cell proliferation.
Computational Description
ROTUNDIFOLIA4 (ROT4); CONTAINS InterPro DOMAIN/s: DVL (InterPro:IPR012552); BEST Arabidopsis thaliana protein match is: ROTUNDIFOLIA like 1 (TAIR:AT3G53232.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
Encodes a general sigma factor in chloroplasts and is probably responsible for the recognition of sigma 70 type standard bacteria-type multi-subunit RNA polymerase (PEP) promoters in young cotyledons. It is a substrate for regulatory phosphorylation by cpCK2, a nuclear-coded plastid-targeted casein kinase 2, that has been implicated as a key component in plant sigma factor phosphorylation and transcriptional regulation.
Computational Description
RNApolymerase sigma-subunit F (SIGF); CONTAINS InterPro DOMAIN/s: RNA polymerase sigma factor, region 2 (InterPro:IPR013325), Winged helix-turn-helix transcription repressor DNA-binding (InterPro:IPR011991), RNA polymerase sigma-70 region 3 (InterPro:IPR007624), RNA polymerase sigma-70 (InterPro:IPR014284), RNA polymerase sigma factor, region 3/4 (InterPro:IPR013324), RNA polymerase sigma factor, SigB/SigC/SigD, plastid (InterPro:IPR016262), RNA polymerase sigma-70 factor (InterPro:IPR000943), RNA polymerase sigma-70 region 2 (InterPro:IPR007627), RNA polymerase sigma-70 region 4 (InterPro:IPR007630); BEST Arabidopsis thaliana protein match is: RNApolymerase sigma subunit 2 (TAIR:AT1G08540.1); Has 23918 Blast hits to 23899 proteins in 2801 species: Archae - 0; Bacteria - 17084; Metazoa - 1; Fungi - 2; Plants - 241; Viruses - 15; Other Eukaryotes - 6575 (source: NCBI BLink).