Glutamate-tRNA ligase. Targeted to mitochondria and chloroplast. Its inactivation causes developmental arrest of chloroplasts and mitochondria in Nicotiana benthamiana.
Computational Description
glutamate tRNA synthetase (ERS); FUNCTIONS IN: protein binding, glutamate-tRNA ligase activity; INVOLVED IN: chloroplast organization, glutamyl-tRNA aminoacylation, mitochondrion organization, tRNA aminoacylation, ovule development; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Aminoacyl-tRNA synthetase, class I, conserved site (InterPro:IPR001412), Glutamyl/glutaminyl-tRNA synthetase, class Ic, alpha-bundle domain (InterPro:IPR020061), Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial (InterPro:IPR004527), Glutamyl/glutaminyl-tRNA synthetase, class Ic, N-terminal (InterPro:IPR020060), Aminoacyl-tRNA synthetase, class I, anticodon-binding (InterPro:IPR008925), Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain (InterPro:IPR020058), Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Glutamyl/glutaminyl-tRNA synthetase, class Ic (InterPro:IPR000924), Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 (InterPro:IPR020751); BEST Arabidopsis thaliana protein match is: Glutamyl/glutaminyl-tRNA synthetase, class Ic (TAIR:AT5G26710.1); Has 1807 Blast hits to 1807 proteins in 277 species: Archae - 0; Bacteria - 0; Metazoa - 736; Fungi - 347; Plants - 385; Viruses - 0; Other Eukaryotes - 339 (source: NCBI BLink).
