Encodes a protein with similarity to squalene synthase which catalyzes the first committed step in sterol biosynthesis. To date no experimental evidence exists that SQS2 functions as a squalene synthase and some experiments indicate it does not have this function.
Computational Description
squalene synthase 2 (SQS2); FUNCTIONS IN: farnesyl-diphosphate farnesyltransferase activity; INVOLVED IN: N-terminal protein myristoylation, sterol biosynthetic process; LOCATED IN: integral to membrane; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Terpenoid synthase (InterPro:IPR008949), Farnesyl-diphosphate farnesyltransferase (InterPro:IPR006449), Squalene/phytoene synthase (InterPro:IPR002060); BEST Arabidopsis thaliana protein match is: squalene synthase 1 (TAIR:AT4G34640.1); Has 1176 Blast hits to 1175 proteins in 496 species: Archae - 34; Bacteria - 579; Metazoa - 114; Fungi - 168; Plants - 163; Viruses - 0; Other Eukaryotes - 118 (source: NCBI BLink).