encodes a a novel transcriptional repressor harboring two double-stranded RNA-binding domains and a region homologous to the catalytic domain of RNA polymerase II C-terminal domain phosphatases found in yeast and in animals that regulate gene transcription. Protein exhibits innate phosphatase activity in vitro. Mutants exhibit hyperresponsiveness to ABA, cold, and NaCl.
Computational Description
C-terminal domain phosphatase-like 1 (CPL1); FUNCTIONS IN: double-stranded RNA binding, phosphatase activity, nucleotide phosphatase activity; INVOLVED IN: abscisic acid mediated signaling pathway, negative regulation of transcription, response to abiotic stimulus; LOCATED IN: intracellular; CONTAINS InterPro DOMAIN/s: Double-stranded RNA-binding (InterPro:IPR001159), NLI interacting factor (InterPro:IPR004274); BEST Arabidopsis thaliana protein match is: carboxyl-terminal domain (ctd) phosphatase-like 2 (TAIR:AT5G01270.2); Has 330 Blast hits to 317 proteins in 105 species: Archae - 0; Bacteria - 31; Metazoa - 57; Fungi - 81; Plants - 112; Viruses - 1; Other Eukaryotes - 48 (source: NCBI BLink).
Encodes a putative phosphoinositide-specific phospholipase C. There are two genes called ATPLC1, one corresponding to AT4g38530 (this one) and one corresponding to AT5g58670.
Computational Description
phospholipase C1 (PLC1); FUNCTIONS IN: phospholipase C activity; INVOLVED IN: signal transduction, intracellular signaling pathway, lipid metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Phospholipase C, phosphoinositol-specific, EF-hand-like (InterPro:IPR015359), Phospholipase C, phosphatidylinositol-specific , X domain (InterPro:IPR000909), PLC-like phosphodiesterase, TIM beta/alpha-barrel domain (InterPro:IPR017946), C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding domain, CaLB (InterPro:IPR008973), Phospholipase C, phosphoinositol-specific (InterPro:IPR001192), C2 calcium-dependent membrane targeting (InterPro:IPR000008), Phospholipase C, phosphatidylinositol-specific, Y domain (InterPro:IPR001711); BEST Arabidopsis thaliana protein match is: phospholipase C1 (TAIR:AT5G58670.1); Has 2562 Blast hits to 1935 proteins in 260 species: Archae - 0; Bacteria - 0; Metazoa - 1702; Fungi - 403; Plants - 251; Viruses - 0; Other Eukaryotes - 206 (source: NCBI BLink).
