Encodes a nuclear-localized MAP kinase phosphatase. Plants with reduced levels of MKP2 transcripts are hypersensitive to ozone and ozone-mediated activation of MPK3 and MPK6 is prolonged in these plants.
Computational Description
MAPK phosphatase 2 (MKP2); FUNCTIONS IN: MAP kinase phosphatase activity, protein tyrosine/serine/threonine phosphatase activity; INVOLVED IN: intracellular protein kinase cascade, response to ozone, negative regulation of MAP kinase activity, response to stress; LOCATED IN: nucleus, plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Dual-specific/protein-tyrosine phosphatase, conserved region (InterPro:IPR000387), Dual specificity phosphatase, catalytic domain (InterPro:IPR000340), Dual specificity phosphatase, subgroup, catalytic domain (InterPro:IPR020422); BEST Arabidopsis thaliana protein match is: dual specificity protein phosphatase 1 (TAIR:AT3G23610.2); Has 4168 Blast hits to 4160 proteins in 377 species: Archae - 19; Bacteria - 125; Metazoa - 2129; Fungi - 477; Plants - 302; Viruses - 229; Other Eukaryotes - 887 (source: NCBI BLink).
basic helix-loop-helix (bHLH) DNA-binding superfamily protein
Curator Summary
Encodes a basic helix-loop-helix (bHLH) protein that controls meristemoid differentiation during stomatal development. In the absence of MUTE, meristemoids abort after excessive asymmetric divisions and fail to differentiate stomata.
Computational Description
MUTE (MUTE); CONTAINS InterPro DOMAIN/s: Helix-loop-helix DNA-binding domain (InterPro:IPR001092), Helix-loop-helix DNA-binding (InterPro:IPR011598); BEST Arabidopsis thaliana protein match is: basic helix-loop-helix (bHLH) DNA-binding superfamily protein (TAIR:AT3G24140.1); Has 1269 Blast hits to 1254 proteins in 66 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1269; Viruses - 0; Other Eukaryotes - 0 (source: NCBI BLink).
